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Uroplakin 1B 抗体 (AA 109-229)

The 小鼠 单克隆 anti-Uroplakin 1B antibody is suitable to detect Uroplakin 1B in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7870044
发货至: 中国
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Quick Overview for Uroplakin 1B 抗体 (AA 109-229) (ABIN7870044)

抗原

See all Uroplakin 1B (UPK1B) 抗体
Uroplakin 1B (UPK1B)

适用

  • 58
  • 5
  • 4

宿主

  • 30
  • 28
小鼠

克隆类型

  • 38
  • 20
单克隆

标记

  • 35
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This Uroplakin 1B antibody is un-conjugated

应用范围

  • 32
  • 19
  • 18
  • 18
  • 13
  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

UPK1B-3273
  • 抗原表位

    • 36
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 109-229

    原理

    Uroplakin 1B Antibody / UPK1B (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 109-229) was used at the immunogen for this Uroplakin 1B antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Uroplakin 1B antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Uroplakin 1B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Uroplakin 1B (UPK1B)

    别名

    Uroplakin 1B

    背景

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.

    UniProt

    O75841
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