VEGFC 抗体 (AA 108-223)
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Quick Overview for VEGFC 抗体 (AA 108-223) (ABIN7870024)
抗原
See all VEGFC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 108-223
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原理
- Vegfc Antibody / Vascular endothelial growth factor C
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived mouse recombinant protein (A108-R223) was used as the immunogen for the Vegfc antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Vegfc antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Vegfc antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
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别名
- Vegfc
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背景
- Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family. It is encoded in humans by the VEGFC gene, which is located on chromosome 4q34. Enables vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including negative regulation of osteoblast differentiation, positive regulation of angiogenesis, and positive regulation of mesenchymal stem cell proliferation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor, positive regulation of lymphangiogenesis, and positive regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in several structures, including alimentary system mesentery, brain, cardiovascular system, embryo mesenchyme, and genitourinary system. Used to study hereditary lymphedema. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C).
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UniProt
- P97953
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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