HDAC5 抗体 (AA 102-197)
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Quick Overview for HDAC5 抗体 (AA 102-197) (ABIN7869910)
抗原
See all HDAC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 102-197
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原理
- HDAC5 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids H102-E197 from the human protein were used as the immunogen for the HDAC5 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the HDAC5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HDAC5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HDAC5 (Histone Deacetylase 5 (HDAC5))
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别名
- HDAC5
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背景
- Histone deacetylase 5, also called HDAC5 or KIAA0600, is an enzyme that in humans is encodes by the HDAC5 gene. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. This gene is mapped to 17q21.31. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer.
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UniProt
- Q9UQL6
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
抗原
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