Amphiregulin 抗体 (AA 101-180)
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Quick Overview for Amphiregulin 抗体 (AA 101-180) (ABIN7869891)
抗原
See all Amphiregulin (AREG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-180
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原理
- AREG Antibody / Amphiregulin
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids S101-R180) was used as the immunogen for the AREG antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the AREG antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the AREG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Amphiregulin (AREG)
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别名
- AREG
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背景
- Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.
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UniProt
- P15514
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途径
- RTK signaling, EGFR Signaling Pathway
抗原
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