MUC13 抗体 (AA 100-300)
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Quick Overview for MUC13 抗体 (AA 100-300) (ABIN7869845)
抗原
See all MUC13 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-300
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原理
- Mucin 13 Antibody / MUC13
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纯化方法
- Protein A affinity
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免疫原
- A portion of amino acids 100-300 from human Mucin 13 protein was used as the immunogen for the Mucin 13 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Mucin 13 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Mucin 13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MUC13 (Mucin 13, Cell Surface Associated (MUC13))
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别名
- Mucin 13
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背景
- Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine, serine and proline. Mucin 13 (MUC13), also designated downregulated in colon cancer 1 (DRCC1), is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract, and within goblet cell thecae. Mucin 13 is a cleaved protein, and the b subunit, containing the cytoplasmic tail, can homodimerize.
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UniProt
- Q9H3R2
抗原
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