CD276 抗体 (AA 100-300)
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北京 101111
Quick Overview for CD276 抗体 (AA 100-300) (ABIN7869825)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-300
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原理
- CD276 Antibody / B7-H3
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 100-300 from the human CD276 protein was used as the immunogen for the CD276 antibody.
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亚型
- IgG1, kappa
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anti-CD276 (CD276) (AA 47-219) antibody
CD276 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (C-Term) antibodyCD276 适用: 人, 小鼠 WB, IHC, FACS, IP, ICC, IF (p) 宿主: 兔 Monoclonal BLR025F unconjugated Recombinant Antibody
anti-CD276 (CD276) (AA 29-466) antibodyCD276 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8C1C2 unconjugated
anti-CD276 (CD276) (AA 47-213) antibodyCD276 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 29-465) antibodyCD276 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR026F unconjugated Recombinant Antibody
anti-CD276 (CD276) (AA 29-458) antibodyCD276 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 493-522), (C-Term) antibodyCD276 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB31111 unconjugated
anti-CD276 (CD276) (AA 237-358) antibodyCD276 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-CD276 (CD276) (AA 100-200) antibodyCD276 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) antibodyKD Validated CD276 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB5035 unconjugated Recombinant Antibody
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应用备注
- Optimal dilution of the CD276 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the CD276 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD276
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别名
- CD276
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背景
- T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory molecules. One such molecule, B7-H3 (B7-homolog 3, also designated B7RP-2 and CD276) belongs to the B7 immunoglobulin superfamily. Soluble B7-H3/CD276 binds a putative receptor on activated T-cells that is distinct from CD28, CTLA-4, ICOS and PD-1. Widely expressed on nonlymphoid tissues, it costimulates proliferation of both CD4+ and CD8+ T cells. The ability of B7-H3/CD276 to stimulate Th1 and cytotoxic-T cell responses suggest that it may have antitumor activity. B7-H3 interactions may play a role in regulating cell-mediated immune responses against cancer, implicating B7-H3/CD276 as a potential therapeutic tool.
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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