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CD276 抗体 (AA 100-300)

The 小鼠 单克隆 anti-CD276 antibody (Clone B7H3-4312) (ABIN7869823) specifically detects CD276 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7869823
发货至: 中国
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Quick Overview for CD276 抗体 (AA 100-300) (ABIN7869823)

抗原

See all CD276 抗体
CD276

适用

  • 130
  • 51
  • 15
  • 5
  • 5
  • 3
  • 2
  • 2
  • 1

宿主

  • 67
  • 51
  • 19
  • 9
  • 1
  • 1
小鼠

克隆类型

  • 100
  • 47
  • 1
单克隆

标记

  • 87
  • 10
  • 7
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CD276 antibody is un-conjugated

应用范围

  • 70
  • 36
  • 33
  • 28
  • 23
  • 18
  • 14
  • 13
  • 10
  • 9
  • 4
  • 2
  • 2
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

B7H3-4312
  • 抗原表位

    • 19
    • 15
    • 9
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-300

    原理

    CD276 Antibody / B7-H3

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 100-300) from the human protein was used as the immunogen for the CD276 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the CD276 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CD276 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD276

    别名

    CD276

    背景

    T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory molecules. One such molecule, B7-H3 (B7-homolog 3, also designated B7RP-2) belongs to the B7 immunoglobulin superfamily. Soluble B7-H3 binds a putative receptor on activated T-cells that is distinct from CD28, CTLA-4, ICOS and PD-1. Widely expressed on nonlymphoid tissues, B7-H3 costimulates proliferation of both CD4+ and CD8+ T cells. The ability of B7-H3 to stimulate Th1 and cytotoxic-T cell responses suggest that it may have antitumor activity. B7-H3 interactions may play a role in regulating cell-mediated immune responses against cancer, implicating B7-H3 as a potential therapeutic tool.

    UniProt

    Q5ZPR3

    途径

    Cancer Immune Checkpoints
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