Phospholipase C delta 3 抗体 (AA 10-702)
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Quick Overview for Phospholipase C delta 3 抗体 (AA 10-702) (ABIN7869717)
抗原
See all Phospholipase C delta 3 (PLCd3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-702
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原理
- PLC-delta-3 Antibody / PLCD3
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R10-Q702) was used as the immunogen for the PLC-delta-3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PLC-delta-3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PLC-delta-3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Phospholipase C delta 3 (PLCd3)
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别名
- PLC-delta-3
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背景
- 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 is an enzyme that in humans is encoded by the PLCD3 gene. This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
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UniProt
- Q8N3E9
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途径
- WNT signaling
抗原
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