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VCP 抗体 (AA 10-512)

The 兔 多克隆 anti-VCP antibody is suitable to detect VCP in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for WB, ELISA, FACS 和 IHC (p).
产品编号 ABIN7869711
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for VCP 抗体 (AA 10-512) (ABIN7869711)

抗原

See all VCP 抗体
VCP (Valosin Containing Protein (VCP))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This VCP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 10-512

    原理

    TER ATPase Antibody / VCP / Valosin-containing protein

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids D10-K512) was used as the immunogen for the TER ATPase antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the TER ATPase antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the TER ATPase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    VCP (Valosin Containing Protein (VCP))

    别名

    TER ATPase

    背景

    Valosin-containing protein also called CDC48 is an enzyme that in humans is encoded by the VCP gene. It is a member of the AAA+ (ATPase associated with various activities) protein family. The VCP gene maps to chromosome 9p13.3. It is necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. It is involved in the formation of the transitional endoplasmic reticulum. This gene plays a role in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It also involved in DNA damage response: recruited to double-strand breaks (DSBs) sites in a RNF8- and RNF168-dependent manner and promotes the recruitment of TP53BP1 at DNA damage sites.

    UniProt

    P55072

    途径

    ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway
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