POLR2A/RPB1 抗体 (AA 10-321)
Our Local Distributor
北京 101111
Quick Overview for POLR2A/RPB1 抗体 (AA 10-321) (ABIN7869698)
抗原
See all POLR2A/RPB1 (POLR2A) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 10-321
-
原理
- POLR2A Antibody / RNA polymerase II subunit RPB1
-
纯化方法
- Affinity purified
-
免疫原
- Recombinant human protein (amino acids D10-E321) was used as the immunogen for the POLR2A antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the POLR2A antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the POLR2A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
-
别名
- POLR2A
-
背景
- DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that in humans is encoded by the POLR2A gene. It is mapped to 17p13.1. This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
-
UniProt
- P24928
-
途径
- Regulatory RNA Pathways
抗原
-