NKX2-8 抗体 (AA 10-123)
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Quick Overview for NKX2-8 抗体 (AA 10-123) (ABIN7869675)
抗原
See all NKX2-8 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 10-123
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原理
- NKX2.8 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 10-123) was used as the immunogen for the NKX2.8 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the NKX2.8 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the NKX2.8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- NKX2-8 (NK2 Homeobox 8 (NKX2-8))
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别名
- NKX2.8
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背景
- The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.
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UniProt
- O15522
抗原
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