Recombinant NKX2-8 抗体 (AA 10-123)
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北京 101111
Quick Overview for Recombinant NKX2-8 抗体 (AA 10-123) (ABIN6939494)
抗原
See all NKX2-8 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 10-123
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原理
- Recombinant NKX2.8 Antibody
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特异性
- The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)
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亚型
- IgG, kappa
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应用备注
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Positive Control: Human Liver, Kidney or Thyroid tissue (IHC).
Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- NKX2-8 (NK2 Homeobox 8 (NKX2-8))
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别名
- NKX2-8
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背景
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Homeobox protein NK-2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX2G, NKX2H, OTTHUMP00000027959
Kidney or Thyroid tissue (IHC)., PC3 or MCF-7 cells. Human Liver
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分子量
- 26kDa
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基因ID
- 26257, 234763
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UniProt
- O15522
抗原
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