TFF1 抗体 (AA 1-84)
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北京 101111
Quick Overview for TFF1 抗体 (AA 1-84) (ABIN7869588)
抗原
See all TFF1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-84
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原理
- pS2 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 1-84) from the human protein was used as the immunogen for the pS2 antibody.
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亚型
- IgG2a, kappa
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anti-Trefoil Factor 1 (TFF1) antibody
TFF1 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal TFF1-2133 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 25-84), (pSer2) antibodyTFF1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) antibodyTFF1 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-87) antibodyTFF1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-81) antibodyTFF1 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-84) antibodyTFF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 57-84) antibodyTFF1 适用: 人, Cynomolgus IHC 宿主: 小鼠 Monoclonal GE2-same as R47-94 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-84) antibodyTFF1 适用: 人 IHC, WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-88) antibodyTFF1 适用: 人 IHC 宿主: 小鼠 Monoclonal 482M unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 22-87) antibodyTFF1 适用: 小鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the pS2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the pS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TFF1 (Trefoil Factor 1 (TFF1))
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别名
- pS2
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背景
- It recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60 % of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
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UniProt
- P04155
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途径
- EGFR Signaling Pathway
抗原
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