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FER 抗体 (AA 1-804)

The 兔 多克隆 anti-FER antibody (ABIN7869568) specifically detects FER in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7869568
发货至: 中国
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Quick Overview for FER 抗体 (AA 1-804) (ABIN7869568)

抗原

See all FER 抗体
FER (FER Tyrosine Kinase (FER))

适用

  • 77
  • 65
  • 19
  • 7
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 89
  • 13

克隆类型

  • 88
  • 14
多克隆

标记

  • 54
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
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  • 2
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This FER antibody is un-conjugated

应用范围

  • 87
  • 34
  • 26
  • 26
  • 19
  • 16
  • 13
  • 6
  • 6
  • 4
  • 4
  • 2
  • 2
Western Blotting (WB), ELISA
  • 抗原表位

    • 26
    • 15
    • 11
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 1-804

    原理

    FER Antibody / FPS/FES-Related tyrosine kinase

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids M1-R804) was used as the immunogen for the FER antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the FER antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the FER antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    FER (FER Tyrosine Kinase (FER))

    别名

    FER

    背景

    FER (FPS/FES-Related tyrosine kinase) also known as TYK3, is an enzyme that in humans is encoded by the FER gene. Fer protein is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. By in situ hybridization, Morris et al.(1990) concluded that the FER gene is located at 5q21-q22. Treatment of cells with JMP resulted in the release of FER from the cadherin complex and its accumulation in the integrin complex. The accumulation of FER in the integrin complex and the inhibitory effects of JMP could be reversed with a peptide that mimics the first coiled-coil domain of FER. The results suggested that FER mediates crosstalk between CDH2 and ITGB1. In Fer mutant mice, leukocyte emigration was exaggerated in response to LPS without altering vascular permeability, suggesting that FER has a role in regulating innate immunity.

    UniProt

    P16591
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