USP5 抗体 (AA 1-800)
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Quick Overview for USP5 抗体 (AA 1-800) (ABIN7869566)
抗原
See all USP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-800
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原理
- USP5 Antibody / Ubiquitin carboxyl-terminal hydrolase 5
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids M1-K800 from the human protein were used as the immunogen for the USP5 antibody.
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 5 (USP5) antibody
USP5 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Ubiquitin Specific Peptidase 5 (USP5) (AA 1-280) antibodyUSP5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 5 (USP5) antibodyUSP5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 5 (USP5) (AA 1-800) antibodyUSP5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 5 (USP5) (AA 375-425) antibodyUSP5 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 5 (USP5) (AA 201-500) antibodyUSP5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 5 (USP5) antibodyKD Validated USP5 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2480 unconjugated Recombinant Antibody
anti-Ubiquitin Specific Peptidase 5 (USP5) (AA 59-90), (N-Term) antibodyUSP5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4271 unconjugated
anti-Ubiquitin Specific Peptidase 5 (USP5) (AA 71-180) antibodyUSP5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 5 (USP5) antibodyUSP5 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 13C4 unconjugated
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应用备注
- Optimal dilution of the USP5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the USP5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- USP5 (Ubiquitin Specific Peptidase 5 (USP5))
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别名
- USP5
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背景
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USP5 (Ubiquitin carboxyl-terminal hydrolase 5) is a member of the deubiquitinating enzyme (DUB) family, which plays a central role in regulating protein stability and turnover by processing ubiquitin chains. USP5 specifically disassembles unanchored polyubiquitin chains into monoubiquitin, maintaining a sufficient pool of free ubiquitin necessary for cellular homeostasis. A USP5 antibody is widely used to study protein degradation, ubiquitin recycling, and regulatory pathways involving the proteasome.
USP5, sometimes referred to as Isopeptidase T, functions in close connection with the ubiquitin-proteasome system, a critical mechanism for protein quality control. By hydrolyzing ubiquitin linkages, it prevents the accumulation of free polyubiquitin chains, which could otherwise interfere with proteasomal activity. Using a USP5 antibody enables researchers to evaluate its expression patterns, subcellular localization, and functional involvement in ubiquitin dynamics.
Dysregulation of USP5 has been linked to several disease processes. Elevated USP5 expression has been associated with tumor progression in cancers such as glioblastoma, colorectal cancer, and pancreatic cancer, where it contributes to cell proliferation and survival. It has also been implicated in neurological disorders due to its role in protein turnover, highlighting its importance in both health and disease. Investigating these roles with a USP5 antibody provides valuable insights into its potential as a biomarker or therapeutic target.
NSJ Bioreagents offers a high-quality USP5 antibody validated for applications including western blot, immunohistochemistry, and immunofluorescence. Selecting a USP5 antibody from NSJ Bioreagents ensures reliable results and reproducibility in studies focused on the ubiquitin-proteasome pathway, cancer biology, and protein regulation. -
UniProt
- P45974
抗原
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