HK3 抗体 (AA 1-789)
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Quick Overview for HK3 抗体 (AA 1-789) (ABIN7869557)
抗原
See all HK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-789
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原理
- Hexokinase 3 Antibody / HK3
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纯化方法
- Antigen affinity purified
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免疫原
- A human recombinant partial protein (amino acids M1-K789) was used as the immunogen for the Hexokinase 3 antibody.
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亚型
- IgG
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anti-Hexokinase 3 (White Cell) (HK3) (AA 760-789), (C-Term) antibody
HK3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3916 unconjugated
anti-Hexokinase 3 (White Cell) (HK3) (AA 1-270) antibodyHK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 3 (White Cell) (HK3) (AA 1-923) antibodyHK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hexokinase 3 (White Cell) (HK3) antibodyHK3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 3 (White Cell) (HK3) (AA 1-30), (N-Term) antibodyHK3 适用: 人 WB 宿主: 兔 Polyclonal RB5335 unconjugated
anti-Hexokinase 3 (White Cell) (HK3) (AA 673-903) antibodyHK3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 3 (White Cell) (HK3) (AA 1-923) antibodyHK3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 3 (White Cell) (HK3) (C-Term) antibodyHK3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Hexokinase 3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Hexokinase 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HK3 (Hexokinase 3 (White Cell) (HK3))
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别名
- Hexokinase 3
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背景
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Hexokinase 3 (HK3) is a member of the hexokinase enzyme family, which catalyzes the first committed step in glucose metabolism. Like other isoforms, HK3 phosphorylates glucose to produce glucose-6-phosphate, a critical intermediate in glycolysis and the pentose phosphate pathway. This phosphorylation step traps glucose inside the cell and directs it into energy-producing and biosynthetic pathways. Researchers often use a Hexokinase 3 antibody to study cellular metabolism, energy regulation, and metabolic diseases.
HK3 differs from other hexokinase isoforms in its tissue distribution and regulatory properties. It is predominantly expressed in leukocytes and other hematopoietic cells, suggesting a specialized role in immune cell metabolism. Unlike HK1 and HK2, HK3 does not strongly associate with the outer mitochondrial membrane, which may influence its role in apoptosis and energy regulation. Employing a Hexokinase 3 antibody allows scientists to explore its unique expression patterns and its contributions to both glycolysis and immune cell biology.
Altered expression of HK3 has been observed in cancer and inflammatory conditions, where shifts in glucose metabolism play a role in disease progression. HK3 has also been implicated in oxidative stress responses and metabolic reprogramming of immune cells. As interest in immunometabolism continues to grow, HK3 remains an important protein for research into metabolic regulation and disease. Using a Hexokinase 3 antibody enables reliable detection of this isoform in various biological contexts.
NSJ Bioreagents provides a high-quality Hexokinase 3 antibody validated for applications such as western blot, immunohistochemistry, and immunofluorescence. Choosing a Hexokinase 3 antibody from NSJ Bioreagents ensures consistent performance and reproducible results in studies of glucose metabolism, immunometabolism, and disease mechanisms. -
UniProt
- P52790
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途径
- Carbohydrate Homeostasis, Warburg Effect
抗原
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