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HK3 抗体 (C-Term)

HK3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3916 unconjugated
产品编号 ABIN392753
发货至: 中国
  • 抗原 See all HK3 抗体
    HK3 (Hexokinase 3 (White Cell) (HK3))
    抗原表位
    • 11
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 760-789, C-Term
    适用
    • 53
    • 4
    • 2
    人, 小鼠
    宿主
    • 50
    • 4
    克隆类型
    • 52
    • 2
    多克隆
    标记
    • 28
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HK3 antibody is un-conjugated
    应用范围
    • 35
    • 29
    • 23
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This HK3 (Hexokinase III) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 760-789 amino acids from the C-terminal region of human HK3 (Hexokinase III).
    克隆位点
    RB3916
    亚型
    Ig Fraction
    Top Product
    Discover our top product HK3 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • van der Kooij, Rojas-Charry, Givehchi, Wolf, Bueno, Arndt, Tenzer, Mattioni, Treccani, Hasch, Schmeisser, Vianello, Giacomello, Methner: "Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels." in: Journal of molecular medicine (Berlin, Germany), Vol. 100, Issue 10, pp. 1441-1453, (2022) (PubMed).

    Palmieri, Fitzgerald, Shreeve, Hua, Bronder, Weil, Davis, Stark, Merino, Kurek, Mehdorn, Davis, Steinberg, Meltzer, Aldape, Steeg: "Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis." in: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1438-45, (2009) (PubMed).

  • 抗原
    HK3 (Hexokinase 3 (White Cell) (HK3))
    别名
    HK3 (Hexokinase III) (HK3 产品)
    别名
    HKIII antibody, HXK3 antibody, APS antibody, KLK2A1 antibody, PSA antibody, hK3 antibody, HK III antibody, HK-III antibody, T2E6.5 antibody, T2E6_5 antibody, hexokinase 3 antibody, RNU73859 antibody, hexokinase 3 antibody, kallikrein related peptidase 3 antibody, HK3 antibody, KLK3 antibody, Hk3 antibody, HXK3 antibody
    背景
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).
    分子量
    99025
    基因ID
    3101
    NCBI登录号
    NP_002106
    UniProt
    P52790
    途径
    Carbohydrate Homeostasis, Warburg Effect
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