PKC epsilon 抗体 (AA 1-690)
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Quick Overview for PKC epsilon 抗体 (AA 1-690) (ABIN7869528)
抗原
See all PKC epsilon (PRKCE) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-690
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原理
- PKCE Antibody / PKC epsilon / PRKCE
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids M1-K690) was used as the immunogen for the PKCE antibody.
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亚型
- IgG
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anti-Protein Kinase C, epsilon (PRKCE) (AA 631-737) antibody
PRKCE 适用: 人, 大鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) antibodyPRKCE 适用: 人, 猴, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) antibodyPRKCE 适用: 人, 猴, 犬 IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 488-737) antibodyPRKCE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 403-672) antibodyPRKCE 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) antibodyPRKCE 适用: 人, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 403-672) antibodyPRKCE 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 53-236) antibodyPRKCE 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 301-400) antibodyPRKCE 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 206-236), (N-Term) antibodyPRKCE 适用: 人 WB 宿主: 兔 Polyclonal RB1022 unconjugated
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应用备注
- Optimal dilution of the PKCE antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PKCE antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))
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别名
- PKCE
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背景
- Protein kinase C epsilon type, also known as PKCE, is an enzyme that in humans is encoded by the PRKCE gene. The protein encoded by this gene is one of the PKC family members. PRKCE is mapped to 2p21. This kinase has been shown to be involved in many different cellular functions, such as apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. It has been found that activation of PRKCE can induce VR1 channel activity at room temperature in the absence of any other agonist. PRKCE gene plays a role in apoptosis signaling pathways in thyroid cells and it has been indicated that a naturally occurring PRKCE mutant that functions as a dominant negative can block cell death triggered by a variety of stimuli. Expression of PRKCE inhibits chemotherapy-induced caspase-3 activation and apoptosis, thereby leading to cell survival.
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UniProt
- Q02156
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途径
- TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
抗原
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