CAMK2A 抗体 (AA 1-478)
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Quick Overview for CAMK2A 抗体 (AA 1-478) (ABIN7869399)
抗原
See all CAMK2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-478
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原理
- CAMK II alpha Antibody / CAMK2A
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids M1-H478) was used as the immunogen for the CAMK II alpha antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CAMK II alpha antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CAMK II alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
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别名
- CAMK II alpha
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背景
- Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMKIIa), a.k.a. Ca2+/calmodulin-dependent protein kinase II alpha, is a protein kinase (i.e., an enzyme which phosphorylates proteins) that in humans is encoded by the CAMK2A gene. It is mapped to 5q32. The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
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UniProt
- Q9UQM7
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途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
抗原
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