IKZF3 抗体 (AA 1-456)
Our Local Distributor
北京 101111
Quick Overview for IKZF3 抗体 (AA 1-456) (ABIN7869384)
抗原
See all IKZF3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-456
-
原理
- Aiolos Antibody / IKZF3
-
纯化方法
- Antigen affinity purified
-
免疫原
- An E.coli-derived human recombinant protein (amino acids M1-H456) was used as the immunogen for the Aiolos antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Aiolos antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Aiolos antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
-
别名
- Aiolos
-
背景
- Zinc finger protein Aiolos also known as Ikaros family zinc finger protein 3 is a protein that in humans is encoded by the IKZF3 gene. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
-
UniProt
- Q9UKT9
抗原
-