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ILK 抗体 (AA 1-452)

This 兔 多克隆 antibody specifically detects ILK in WB, ELISA, IF, IHC (p) 和 FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7869383
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for ILK 抗体 (AA 1-452) (ABIN7869383)

抗原

See all ILK 抗体
ILK (Integrin-Linked Kinase (ILK))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ILK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-452

    原理

    Integrin Linked Kinase Antibody / ILK

    纯化方法

    Affinity purified

    免疫原

    An E. coli-derived human protein (amino acids M1-K452) was used as the immunogen for the Integrin Linked Kinase antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Integrin Linked Kinase antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Integrin Linked Kinase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ILK (Integrin-Linked Kinase (ILK))

    别名

    Integrin Linked Kinase

    背景

    ILK, also known as Integrin-linked kinase, is a serine-threonine protein kinase. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/ threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.

    UniProt

    Q13418

    途径

    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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