PAX6 抗体 (AA 1-401)
Our Local Distributor
北京 101111
Quick Overview for PAX6 抗体 (AA 1-401) (ABIN7869319)
抗原
See all PAX6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-401
-
原理
- Zebrafish Pax6 Antibody / Pax6a / Pax6b
-
纯化方法
- Antigen affinity chromatography
-
免疫原
- E. coli-derived zebrafish Pax6 recombinant protein (amino acids M1-M401) was used as the immunogen for the Zebrafish Pax6 antibody. This antibody will detect isoforms a & b.
-
亚型
- Ig Fraction
-
-
anti-Paired Box 6 (PAX6) (AA 1-122) antibody
PAX6 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 1F6G2 unconjugated
anti-Paired Box 6 (PAX6) (AA 51-150) antibodyPAX6 适用: 人, 小鼠, 大鼠 FACS, ELISA, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15517 unconjugated
anti-Paired Box 6 (PAX6) (AA 183-210) antibodyPAX6 适用: 人 WB, IHC, IF, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-422) antibodyPAX6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 183-210) antibodyPAX6 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB21476 unconjugated
anti-Paired Box 6 (PAX6) (AA 195-233), (Middle Region) antibodyPAX6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-422) antibodyPAX6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-300) antibodyPAX6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the Zebrafish Pax6 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Zebrafish Pax6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- PAX6 (Paired Box 6 (PAX6))
-
别名
- Pax6
-
背景
-
Paired box protein 6 (Pax6) is a highly conserved transcription factor that plays a central role in the development of the eye, central nervous system, and pancreas. In zebrafish (Danio rerio), Pax6 is encoded by two paralogous genes, pax6a and pax6b, both of which are essential for ocular morphogenesis, neurogenesis, and endocrine cell differentiation.
During embryogenesis, zebrafish Pax6 is expressed in the forebrain, optic vesicles, retina, and spinal cord, where it regulates the expression of genes critical for cell fate determination and tissue patterning. Pax6 is a key regulator of eye field specification and is required for the proper formation of structures such as the lens, retina, and optic tectum. In addition, it contributes to pancreatic islet cell development, particularly in the differentiation of insulin-producing Beta-cells.
Given its evolutionary conservation and well-characterized functions, zebrafish Pax6 is widely used as a model for studying ocular development, neural differentiation, congenital eye disorders (e.g., aniridia), and transcriptional control of organogenesis.
-
UniProt
- P26630
-
途径
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
-
