PAX6 抗体
(3 references)-
- 抗原 See all PAX6 抗体
- PAX6 (Paired Box 6 (PAX6))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PAX6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human PAX6 expressed in E. coli.
- 克隆位点
- 1C8
- 亚型
- IgG1
- Top Product
- Discover our top product PAX6 Primary Antibody
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anti-Paired Box 6 (PAX6) (AA 1-122) antibody
PAX6 适用: 人 WB, ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 1F6G2 unconjugated
anti-Paired Box 6 (PAX6) (AA 51-150) antibodyPAX6 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 183-210) antibodyPAX6 适用: 人 WB, IF, ELISA, FACS, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-422) antibodyPAX6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 195-233), (Middle Region) antibodyPAX6 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15517 unconjugated
anti-Paired Box 6 (PAX6) (AA 1-300) antibodyPAX6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-422) antibodyPAX6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-300) antibodyPAX6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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: "The beta subunit of voltage-gated Ca2+ channels interacts with and regulates the activity of a novel isoform of Pax6." in: The Journal of biological chemistry, Vol. 285, Issue 4, pp. 2527-36, (2010) (PubMed).
: "Detailed ophthalmologic evaluation of 43 individuals with PAX6 mutations." in: Investigative ophthalmology & visual science, Vol. 50, Issue 6, pp. 2581-90, (2009) (PubMed).
: "PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene." in: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27524-32, (2009) (PubMed).
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: "The beta subunit of voltage-gated Ca2+ channels interacts with and regulates the activity of a novel isoform of Pax6." in: The Journal of biological chemistry, Vol. 285, Issue 4, pp. 2527-36, (2010) (PubMed).
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- 抗原
- PAX6 (Paired Box 6 (PAX6))
- 别名
- PAX6 (PAX6 产品)
- 别名
- pax6 antibody, an2 antibody, mgda antibody, wagr antibody, pax-6 antibody, pax6a antibody, xpax6 antibody, XLPAX6 antibody, MGC52531 antibody, PAX-6 antibody, AN antibody, AN2 antibody, D11S812E antibody, MGDA antibody, WAGR antibody, Pax-6 antibody, pax6b antibody, 1500038E17Rik antibody, AEY11 antibody, Dey antibody, Gsfaey11 antibody, Sey antibody, PAXZF-A antibody, Pax6.1 antibody, cb280 antibody, fc20e07 antibody, pax-a antibody, pax[zf-a] antibody, paxzfa antibody, wu:fc20e07 antibody, zfpax-6a antibody, zfpax-6b antibody, paired box 6 antibody, paired box 6 L homeolog antibody, paired box 6 S homeolog antibody, paired box 6a antibody, PAX6 antibody, pax6 antibody, Pax6 antibody, pax6.L antibody, pax6.S antibody, pax6a antibody
- 背景
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Description: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells .PAX6 is the most researched of the PAX genes and appears throughout the literature as a "master control" gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. This transcription factor is most famous for its use in the interspecifically induced expression of ectopic eyes and is of medical importance because heterozygous mutants produce a wide spectrum of ocular defects such as Aniridia in humans. This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.
Aliases: AN, AN2, MGDA, WAGR, D11S812E, MGC17209, PAX6
- 分子量
- 46 kDa
- 基因ID
- 5080
- HGNC
- 5080
- 途径
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
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