Aurora A 抗体 (AA 1-395)
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北京 101111
Quick Overview for Aurora A 抗体 (AA 1-395) (ABIN7869297)
抗原
See all Aurora A (AURKA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-395
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原理
- Ark-1 Antibody / Aurora-related kinase 1 / Aurka
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant mouse protein (amino acids M1-S395) was used as the immunogen for the Ark-1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Ark-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Ark-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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别名
- Ark-1
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背景
- AURKA (Aurora kinase A), also called ARK-1 (Aurora-related kinase 1), AurA, AIK, AURORA2, BTAK, PPP1R47, STK7, STK15, and STK6 is a mitotic centrosomal protein kinase. The main role of AURKA/ARK-1 in tumor development is in controlling chromosome segregation during mitosis. Aurora A / Aurora-related kinase 1 is a member of a family of mitotic serine/threonine kinases. The AURKA gene is overexpressed in many human cancers. Ectopic overexpression in mammalian cells induces centrosome amplification, chromosome instability, and oncogenic transformation, a phenotype characteristic of loss-of-function mutations of p53.
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UniProt
- P97477
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途径
- Cell Division Cycle, Asymmetric Protein Localization
抗原
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