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DNMT3L 抗体 (AA 1-386)

This 兔 多克隆 antibody specifically detects DNMT3L in WB, ELISA 和 FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7869281
发货至: 中国
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Quick Overview for DNMT3L 抗体 (AA 1-386) (ABIN7869281)

抗原

See all DNMT3L (TRDMT1) 抗体
DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

适用

人, 小鼠, 大鼠

宿主

  • 67
  • 11

克隆类型

  • 69
  • 9
多克隆

标记

  • 35
  • 6
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DNMT3L antibody is un-conjugated

应用范围

  • 62
  • 38
  • 15
  • 13
  • 13
  • 8
  • 6
  • 5
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-386

    原理

    DNMT3L Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human DNMT3L protein (amino acids M1-L386) was used as the immunogen for the DNMT3L antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the DNMT3L antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the DNMT3L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

    别名

    DNMT3L

    背景

    DNA (cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    UniProt

    Q9UJW3
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