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DUSP6 抗体 (AA 1-381)

This 兔 多克隆 antibody specifically detects DUSP6 in WB, ELISA, IF, FACS 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7869275
发货至: 中国
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Quick Overview for DUSP6 抗体 (AA 1-381) (ABIN7869275)

抗原

See all DUSP6 抗体
DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

适用

  • 103
  • 70
  • 63
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 91
  • 11
  • 2
  • 1

克隆类型

  • 76
  • 29
多克隆

标记

  • 44
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DUSP6 antibody is un-conjugated

应用范围

  • 71
  • 31
  • 26
  • 25
  • 16
  • 15
  • 12
  • 11
  • 10
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-381

    原理

    DUSP6 Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids M1-T381) was used as the immunogen for the DUSP6 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the DUSP6 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the DUSP6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

    别名

    DUSP6

    背景

    Dual specificity phosphatase 6 (DUSP6) is an enzyme that in humans is encoded by the DUSP6 gene. The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene.

    UniProt

    Q16828

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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