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DUSP6 抗体 (N-Term)

DUSP6 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB36744 unconjugated
产品编号 ABIN1539487
发货至: 中国
  • 抗原 See all DUSP6 抗体
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    抗原表位
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 59-88, N-Term
    适用
    • 91
    • 58
    • 52
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 79
    • 11
    • 2
    • 1
    克隆类型
    • 73
    • 20
    多克隆
    标记
    • 41
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP6 antibody is un-conjugated
    应用范围
    • 64
    • 35
    • 15
    • 14
    • 11
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    B
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DUSP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the N-terminal region of human DUSP6.
    克隆位点
    RB36744
    亚型
    Ig Fraction
    Top Product
    Discover our top product DUSP6 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    DUSP6 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    别名
    DUSP6 (DUSP6 产品)
    别名
    HH19 antibody, MKP3 antibody, PYST1 antibody, 1300019I03Rik antibody, MKP-3 antibody, Mkp3 antibody, wu:fd99d09 antibody, mkp3 antibody, pyst1 antibody, DUSP6 antibody, dusp6 antibody, dual specificity phosphatase 6 antibody, dual specificity phosphatase 6 L homeolog antibody, Dual specificity protein phosphatase 6 antibody, DUSP6 antibody, Dusp6 antibody, dusp6 antibody, dusp6.L antibody, dus6 antibody
    背景
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
    分子量
    42320
    基因ID
    1848
    NCBI登录号
    NP_001937, NP_073143
    UniProt
    Q16828
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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