PAX6 抗体 (N-Term)
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北京 101111
Quick Overview for PAX6 抗体 (N-Term) (ABIN7869161)
抗原
See all PAX6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-300, N-Term
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原理
- PAX-6 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant fragment (N-terminus, aa 1-300) was used as the immunogen for the PAX-6 antibody.
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亚型
- IgG1, kappa
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anti-Paired Box 6 (PAX6) (AA 1-122) antibody
PAX6 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 1F6G2 unconjugated
anti-Paired Box 6 (PAX6) (AA 51-150) antibodyPAX6 适用: 人, 小鼠, 大鼠 FACS, ELISA, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15517 unconjugated
anti-Paired Box 6 (PAX6) (AA 183-210) antibodyPAX6 适用: 人 WB, IHC, IF, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 352-380) antibodyPAX6 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-422) antibodyPAX6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 183-210) antibodyPAX6 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB21476 unconjugated
anti-Paired Box 6 (PAX6) (AA 195-233), (Middle Region) antibodyPAX6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-422) antibodyPAX6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Paired Box 6 (PAX6) (AA 1-300) antibodyPAX6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Optimal dilution of the PAX-6 antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the PAX-6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- PAX6 (Paired Box 6 (PAX6))
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别名
- PAX-6
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背景
- Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
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UniProt
- P26367
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途径
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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