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PAX6 抗体 (AA 1-300)

The 小鼠 单克隆 anti-PAX6 antibody (Clone PAX6-7705) (ABIN7869148) specifically detects PAX6 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7869148
发货至: 中国
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Quick Overview for PAX6 抗体 (AA 1-300) (ABIN7869148)

抗原

See all PAX6 抗体
PAX6 (Paired Box 6 (PAX6))

适用

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宿主

  • 120
  • 66
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小鼠

克隆类型

  • 105
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单克隆

标记

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This PAX6 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

PAX6-7705
  • 抗原表位

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    AA 1-300

    原理

    PAX6 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein (within amino acids 1-300) from the human protein was used as the immunogen for the PAX6 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PAX6 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the PAX6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PAX6 (Paired Box 6 (PAX6))

    别名

    PAX6

    背景

    Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.

    UniProt

    P26367

    途径

    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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