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ACE2 抗体 (AA 1-300)

The 小鼠 单克隆 anti-ACE2 antibody (Clone ACE2-7202) (ABIN7869112) specifically detects ACE2 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7869112
发货至: 中国
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Quick Overview for ACE2 抗体 (AA 1-300) (ABIN7869112)

抗原

See all ACE2 抗体
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ACE2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

ACE2-7202
  • 抗原表位

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    AA 1-300

    原理

    ACE2 Antibody / Angiotensin-Converting Enzyme 2 (azide and preservative free)

    纯化方法

    Protein G affinity

    免疫原

    A portion of amino acids 1-300 from human ACE2 was used as the immunogen for the ACE2 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the ACE2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the ACE2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    别名

    ACE2

    背景

    Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

    UniProt

    Q9BYF1

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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