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BLK 抗体 (AA 1-30)

The 兔 多克隆 anti-BLK antibody is suitable to detect BLK in samples from 人 和 小鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN7869081
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BLK 抗体 (AA 1-30) (ABIN7869081)

抗原

See all BLK 抗体
BLK (B Lymphoid Tyrosine Kinase (BLK))

适用

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人, 小鼠

宿主

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  • 9
  • 1

克隆类型

  • 56
  • 10
多克隆

标记

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This BLK antibody is un-conjugated

应用范围

  • 50
  • 35
  • 28
  • 13
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  • 5
  • 3
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  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 9
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    • 5
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    • 3
    • 2
    • 2
    • 2
    • 1
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    AA 1-30

    原理

    BLK Antibody / B lymphocyte kinase

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 1-30 from the human protein was used as the immunogen for the BLK antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the BLK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the BLK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    BLK (B Lymphoid Tyrosine Kinase (BLK))

    别名

    BLK

    背景

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

    UniProt

    P51451

    途径

    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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