NQO1 抗体 (AA 1-274)
Our Local Distributor
北京 101111
Quick Overview for NQO1 抗体 (AA 1-274) (ABIN7869027)
抗原
See all NQO1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-274
-
原理
- NQO1 Antibody
-
纯化方法
- Affinity purified
-
免疫原
- Amino acids M1-K274 from the human protein were used as the immunogen for the NQO1 antibody.
-
亚型
- IgG
-
-
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) antibody
NQO1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 2-274) antibodyNQO1 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (C-Term) antibodyVerified NQO1 适用: 人, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 1-274) antibodyNQO1 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 1E3-A6 unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 1-274) antibodyNQO1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (C-Term) antibodyNQO1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 2-273) antibodyNQO1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 2-274) antibodyNQO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 1-50) antibodyNQO1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 118-144) antibodyNQO1 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the NQO1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the NQO1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
-
别名
- NQO1
-
背景
-
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a cytosolic flavoprotein that plays a central role in cellular defense against oxidative stress. As a 2-electron reductase, NQO1 catalyzes the reduction of quinones to hydroquinones, thereby preventing the formation of reactive oxygen species through redox cycling. This detoxifying activity contributes to the maintenance of redox homeostasis and protection of cells from oxidative damage. Research with an NQO1 antibody has provided valuable insights into its functions in normal physiology and disease.
NQO1 expression is regulated by the Nrf2 pathway and is upregulated under stress conditions as part of the antioxidant response. Elevated levels of this enzyme have been reported in various cancers, suggesting a dual role in both cytoprotection and tumor progression. Studies using an NQO1 antibody have linked the protein to drug metabolism, chemoresistance, and its potential as a therapeutic target. Beyond oncology, NQO1 has been studied in relation to cardiovascular disease, neurodegeneration, and aging.
The enzyme also stabilizes certain proteins by protecting them from proteasomal degradation, further highlighting its regulatory importance in cell survival pathways. Given these diverse roles, the use of an NQO1 antibody is valuable for detecting protein expression across tissues, evaluating stress responses, and exploring disease-specific alterations. NSJ Bioreagents offers high-quality NQO1 antibody reagents designed for applications including western blot, immunohistochemistry, and immunofluorescence, enabling researchers to further define the biological significance of this multifunctional protein. -
UniProt
- P15559
抗原
-
