ANAPC5 抗体 (AA 1-266)
Our Local Distributor
北京 101111
Quick Overview for ANAPC5 抗体 (AA 1-266) (ABIN7869004)
抗原
See all ANAPC5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-266
-
原理
- Apc5 Antibody / Anaphase-promoting complex subunit 5
-
纯化方法
- Affinity purified
-
免疫原
- A human recombinant partial protein (amino acids M1-D266) was used as the immunogen for the Apc5 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Apc5 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Apc5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))
-
别名
- Apc5
-
背景
- Anaphase-promoting complex subunit 5 is an enzyme that in humans is encoded by the ANAPC5 gene. This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
-
UniProt
- Q9UJX4
-
途径
- M Phase
抗原
-