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ANAPC5 抗体 (AA 1-266)

The 兔 多克隆 anti-ANAPC5 antibody (ABIN7869004) specifically detects ANAPC5 in WB, ELISA, FACS 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7869004
发货至: 中国
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Quick Overview for ANAPC5 抗体 (AA 1-266) (ABIN7869004)

抗原

See all ANAPC5 抗体
ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

适用

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宿主

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克隆类型

  • 55
多克隆

标记

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This ANAPC5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-266

    原理

    Apc5 Antibody / Anaphase-promoting complex subunit 5

    纯化方法

    Affinity purified

    免疫原

    A human recombinant partial protein (amino acids M1-D266) was used as the immunogen for the Apc5 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Apc5 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Apc5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

    别名

    Apc5

    背景

    Anaphase-promoting complex subunit 5 is an enzyme that in humans is encoded by the ANAPC5 gene. This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

    UniProt

    Q9UJX4

    途径

    M Phase
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