TARDBP 抗体 (AA 1-264)
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Quick Overview for TARDBP 抗体 (AA 1-264) (ABIN7869002)
抗原
See all TARDBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-264
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原理
- TARDBP Antibody / TAR DNA binding protein / TDP43
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids M1-H264) was used as the immunogen for the TARDBP antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TARDBP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TARDBP Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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别名
- TARDBP
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背景
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
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UniProt
- Q13148
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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