Prohibitin 抗体 (AA 1-257)
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Quick Overview for Prohibitin 抗体 (AA 1-257) (ABIN7868992)
抗原
See all Prohibitin (PHB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-257
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原理
- PHB Antibody / Prohibitin
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M1-I257) was used as the immunogen for the PHB antibody.
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亚型
- IgG
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anti-Prohibitin (PHB) (AA 1-272) antibody
PHB 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F4-2B2 unconjugated
anti-Prohibitin (PHB) antibodyPHB 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H7 unconjugated
anti-Prohibitin (PHB) antibodyKO Validated PHB 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 177-272) antibodyPHB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal PHB-3194 unconjugated
anti-Prohibitin (PHB) (AA 73-272) antibodyPHB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal PHB-3231 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal PHB-3230 unconjugated
anti-Prohibitin (PHB) (AA 89-117) antibodyPHB 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB17513 unconjugated
anti-Prohibitin (PHB) (AA 167-261) antibodyPHB 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal PHB-1881 unconjugated
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应用备注
- Optimal dilution of the PHB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PHB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Prohibitin (PHB)
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别名
- PHB
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背景
- PHB (Prohibitin), also known as PHB1, is a protein that in humans is encoded by the PHB gene. White et al.(1991) mapped the PHB gene to chromosome 17 by analysis of human-mouse somatic cell hybrid cell lines using a genomic fragment of human prohibitin DNA isolated from a library using the rat prohibitin cDNA clone. By in situ hybridization, they localized the gene to 17q21. Sato et al.(1992) isolated the human homolog of the rat prohibitin gene and mapped it to 17q12-q21 by in situ hybridization. Proliferation of tumor cells depends on new blood vessel formation(angiogenesis) that accompanies malignant progression. Anticancer therapies using angiogenesis inhibitors or cytotoxic agents targeted to the vasculature of tumors have been evaluated in clinical trials. Although white fat is a nonmalignant tissue, it has the capability to quickly proliferate and expand. Furthermore, it is highly vascularized. Rupnick et al.(2002) showed that nonspecific angiogenesis inhibitors can prevent the development of obesity of mice.
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UniProt
- P35232
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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