EGLN1 抗体 (AA 1-24)
Our Local Distributor
北京 101111
Quick Overview for EGLN1 抗体 (AA 1-24) (ABIN7868899)
抗原
See all EGLN1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- AA 1-24
-
原理
- EGLN1 Antibody / PHD2 (azide and preservative free)
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Amino acids 1-24 of human PHD2/EGLN1 were used as the immunogen for the EGLN1 antibody.
-
亚型
- IgG1, kappa
-
-
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-426) antibody
KO Validated EGLN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 42-140) antibodyEGLN1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 272-355) antibodyEGLN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (Internal Region) antibodyEGLN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 301-426) antibodyEGLN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) antibodyEGLN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (C-Term) antibodyEGLN1 适用: 人, 小鼠, 大鼠, 兔, 犬, 猴, Cow, 豚鼠, 马, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-24) antibodyEGLN1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 366G-76-3 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-50) antibodyEGLN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 301-426) antibodyEGLN1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the EGLN1 / PHD2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the EGLN1 / PHD2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
-
别名
- EGLN1
-
背景
- 366G/76/3 recognises human prolyl hydroxylase 2 (PHD2), a 46 kDa enzyme expressed abundantly in all tissues with the highest expression in testis. Hypoxia inducible factor-1 (HIF-1) is a transcriptional complex, consisting of an alpha and beta subunit, which plays a key role in coordinating the cellular response to hypoxia. During normal oxygen conditions, the alpha subunit of HIF-1 is rapidly degraded, however when hypoxia occurs this degradation is suppressed and HIF-1 activates the transcription of various genes important for survival and adaptation to hypoxia. Prolyl hydroxylase 2 catalyses the hydroxylation of specific prolyl residues within the HIF-1 alpha subunit, thereby targeting this subunit for degradation.
-
UniProt
- Q9GZT9
-
途径
- cAMP Metabolic Process, Warburg Effect
抗原
-
