CXCR2 抗体 (AA 1-216)
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Quick Overview for CXCR2 抗体 (AA 1-216) (ABIN7868833)
抗原
See all CXCR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-216
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原理
- CXCR2 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M1-Q216) was used as the immunogen for the CXCR2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CXCR2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CXCR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
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别名
- CXCR2
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背景
- CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
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UniProt
- P25025
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途径
- cAMP Metabolic Process
抗原
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