ILK 抗体 (AA 1-203)
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Quick Overview for ILK 抗体 (AA 1-203) (ABIN7868812)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-203
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原理
- Zebrafish Integrin-linked kinase Antibody / ILK
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Integrin-linked kinase recombinant protein (amino acids M1-H203) was used as the immunogen for the Zebrafish Integrin-linked kinase antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Integrin-linked kinase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Integrin-linked kinase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ILK (Integrin-Linked Kinase (ILK))
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别名
- Integrin-linked kinase
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背景
- ILK, also known as Integrin-linked kinase, is a serine-threonine protein kinase. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/ threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.
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UniProt
- Q6PHD6
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途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
抗原
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