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PLK1 抗体 (AA 1-200)

This 小鼠 单克隆 antibody specifically detects PLK1 in ELISA 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7868708
发货至: 中国
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中国
北京 101111
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Room 801-803
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Quick Overview for PLK1 抗体 (AA 1-200) (ABIN7868708)

抗原

See all PLK1 抗体
PLK1 (Polo-Like Kinase 1 (PLK1))

适用

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宿主

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小鼠

克隆类型

  • 108
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单克隆

标记

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This PLK1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

PLK1-7122
  • 抗原表位

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    AA 1-200

    原理

    Polo like kinase 1 Antibody / PLK1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment of human protein (within amino acids 1-200) was used as the immunogen for the Polo like kinase 1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Polo like kinase 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Polo like kinase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PLK1 (Polo-Like Kinase 1 (PLK1))

    别名

    Polo like kinase 1

    背景

    Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle, Plk protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.

    UniProt

    P53350

    途径

    Cell Division Cycle, M Phase
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