PLK1 抗体 (AA 1-200)
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Quick Overview for PLK1 抗体 (AA 1-200) (ABIN7868708)
抗原
See all PLK1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-200
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原理
- Polo like kinase 1 Antibody / PLK1 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment of human protein (within amino acids 1-200) was used as the immunogen for the Polo like kinase 1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Polo like kinase 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Polo like kinase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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别名
- Polo like kinase 1
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背景
- Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle, Plk protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.
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UniProt
- P53350
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途径
- Cell Division Cycle, M Phase
抗原
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