Recombinant LAMP3 抗体 (AA 1-200)
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Quick Overview for Recombinant LAMP3 抗体 (AA 1-200) (ABIN7868636)
抗原
See all LAMP3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-200
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原理
- Recombinant LAMP-3 Antibody / CD63 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment (within amino acids 1-200) of human CD63 protein was used as the immunogen for the recombinant LAMP-3 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the recombinant LAMP-3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant LAMP-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))
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别名
- LAMP-3
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背景
- This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
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UniProt
- P08962
抗原
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