KNG1 抗体 (AA 1-200)
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北京 101111
Quick Overview for KNG1 抗体 (AA 1-200) (ABIN7868631)
抗原
See all KNG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Bradykinin Antibody / KNG1 / Kininogen 1
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Bradykinin antibody.
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亚型
- IgG1
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anti-Kininogen 1 (KNG1) (AA 214-475) antibody
KNG1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 225-407) antibodyKNG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 390-644) antibodyKNG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 268-540) antibodyKNG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (N-Term) antibodyKNG1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 19-380) antibodyKNG1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 148-427) antibodyKNG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 138-166), (N-Term) antibodyKNG1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18408 unconjugated
anti-Kininogen 1 (KNG1) (AA 22-379) antibodyKNG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 322-427) antibodyKNG1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4A1 unconjugated
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应用备注
- Optimal dilution of the Bradykinin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Bradykinin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- KNG1 (Kininogen 1 (KNG1))
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别名
- Bradykinin
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背景
- Kininogen is a 644 amino acid precursor protein that is expressed by the KNG1 gene and is secreted into blood plasma. Due to alternative splicing events, several Kininogen protein derivatives exist, including Kininogen LC and Kininogen HC, both of which are produced from the Kininogen precursor and exhibit different functions throughout the cell. Kininogen HC plays an important role in blood coagulation by helping to ensure that prekallikrein and Factor XI (both of which are involved in blood coagulation) are properly situated for interaction with Factor XII. Kininogen HC releases a smaller, active protein known as bradykinin, which plays a role in smooth muscle contraction, induction of hypotension, regulation of blood glucose levels, stimulation of nociceptors and overall mediation of inflammatory responses throughout the cell. In contrast to Kininogen HC, which is involved in blood clotting, Kininogen LC is primarily associated with inhibition of thrombocyte aggregation and also functions as a strong inhibitor of cysteine proteinases.
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UniProt
- P01042
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途径
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
抗原
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