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Caspase 7 抗体 (AA 1-200)

This 小鼠 单克隆 antibody specifically detects Caspase 7 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7868399
发货至: 中国
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Quick Overview for Caspase 7 抗体 (AA 1-200) (ABIN7868399)

抗原

See all Caspase 7 (CASP7) 抗体
Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

适用

  • 126
  • 72
  • 41
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 122
  • 26
  • 1
小鼠

克隆类型

  • 90
  • 59
单克隆

标记

  • 86
  • 12
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Caspase 7 antibody is un-conjugated

应用范围

  • 123
  • 81
  • 30
  • 27
  • 25
  • 22
  • 21
  • 13
  • 13
  • 4
  • 4
  • 3
  • 3
  • 3
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CASP7-9054
  • 抗原表位

    • 18
    • 15
    • 15
    • 12
    • 10
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200

    原理

    CASP7 Antibody / Caspase 7

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment (within amino acids 1-200) of human CASP7 protein was used as the immunogen for the CASP7 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the CASP7 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CASP7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

    别名

    CASP7

    背景

    A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, CED-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. CED-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli.

    UniProt

    P55210

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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