Ki-67 抗体 (AA 1-200)
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北京 101111
Quick Overview for Ki-67 抗体 (AA 1-200) (ABIN7868370)
抗原
See all Ki-67 (MKI67) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-200
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原理
- Ki-67 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant human Ki67 protein fragment (within amino acids 1-200) was used as the immunogen for the Ki-67 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Ki-67 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Ki-67 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
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别名
- Ki-67
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背景
- Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.
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UniProt
- P46013
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途径
- Glycosaminoglycan Metabolic Process
抗原
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