Angiopoietin 1 抗体 (AA 1-200)
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Quick Overview for Angiopoietin 1 抗体 (AA 1-200) (ABIN7868368)
抗原
See all Angiopoietin 1 (ANGPT1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-200
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原理
- Angiopoietin 1 Antibody / ANGPT1 (azide and preservative free)
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纯化方法
- Protein G affinity
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免疫原
- A portion of amino acids 1-200 from human AGPAT1 protein was used as the immunogen for the Angiopoietin 1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Angiopoietin 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Angiopoietin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Angiopoietin 1 (ANGPT1)
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别名
- Angiopoietin 1
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背景
- This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema.
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UniProt
- Q15389
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途径
- RTK signaling, Glycosaminoglycan Metabolic Process
抗原
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