ASCL1 抗体 (AA 1-196)
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Quick Overview for ASCL1 抗体 (AA 1-196) (ABIN7868352)
抗原
See all ASCL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-196
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原理
- Zebrafish Ascl1a Antibody / Achaete-scute homolog 1
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Ascl1a recombinant protein (amino acids M1-F196) was used as the immunogen for the Zebrafish Ascl1a antibody.
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亚型
- Ig Fraction
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anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (C-Term) antibody
ASCL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 186-236) antibodyASCL1 适用: 人, 小鼠 WB, IHC, ICC, IP, FACS 宿主: 兔 Monoclonal BLR164J unconjugated Recombinant Antibody
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 151-236) antibodyASCL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 137-236) antibodyASCL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) antibodyASCL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (N-Term) antibodyASCL1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 84-236) antibodyASCL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 137-236) antibodyASCL1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D9 unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 48-97) antibodyASCL1 适用: 人, Cow, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (AA 137-236) antibodyASCL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Ascl1a antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Ascl1a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
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别名
- Ascl1a
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背景
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Achaete-scute family bHLH transcription factor 1a (Ascl1a) is a basic helix-loop-helix (bHLH) transcription factor that plays a crucial role in neurogenesis and cell fate determination. In zebrafish (Danio rerio), Ascl1a is a key regulator of neural progenitor proliferation and differentiation, particularly within the central nervous system, retina, and intestinal epithelium.
Ascl1a acts downstream of proneural signaling pathways and promotes the commitment of progenitor cells to a neuronal lineage. It is expressed in neural precursor cells during embryonic development and is reactivated in regenerative contexts. In the zebrafish retina and brain, Ascl1a is essential for the regeneration of neurons following injury, making it a prominent factor in regenerative neurobiology.
Zebrafish Ascl1a is widely used as a model for studying the molecular mechanisms of neuronal differentiation, stem cell biology, and tissue regeneration. Its expression is tightly regulated by signaling pathways such as Notch, and its function is conserved across vertebrates, including in mammalian neurogenesis.
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UniProt
- Q90259
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途径
- Dopaminergic Neurogenesis
抗原
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