NUMA1 抗体 (AA 1-1954)
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Quick Overview for NUMA1 抗体 (AA 1-1954) (ABIN7868351)
抗原
See all NUMA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-1954
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原理
- NUMA1 Antibody / Nuclear mitotic apparatus protein 1
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (M1-E1954) was used as the immunogen for the NUMA1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NUMA1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NUMA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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别名
- NUMA1
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背景
- Nuclear mitotic apparatus protein 1 is a protein that in humans is encoded by the NUMA1 gene. This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.
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UniProt
- Q14980
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途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
抗原
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