SNAIL 抗体 (AA 1-170)
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Quick Overview for SNAIL 抗体 (AA 1-170) (ABIN7868241)
抗原
See all SNAIL (SNAI1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-170
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原理
- SNAI1 Antibody / SNAIL
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M1-K170) was used as the immunogen for the SNAI1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SNAI1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SNAI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SNAIL (SNAI1)
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别名
- SNAI1
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背景
- The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition.
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UniProt
- O95863
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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