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Cofilin 2 抗体 (AA 1-166)

The 小鼠 单克隆 anti-Cofilin 2 antibody (Clone CFL2-9963) (ABIN7868233) specifically detects Cofilin 2 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7868233
发货至: 中国
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Quick Overview for Cofilin 2 抗体 (AA 1-166) (ABIN7868233)

抗原

See all Cofilin 2 (CFL2) 抗体
Cofilin 2 (CFL2)

适用

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宿主

  • 48
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  • 1
小鼠

克隆类型

  • 49
  • 6
单克隆

标记

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This Cofilin 2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CFL2-9963
  • 抗原表位

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    • 2
    • 1
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    AA 1-166

    原理

    Cofilin 2 Antibody / CFL2

    纯化方法

    Protein G affinity

    免疫原

    A portion of amino acids 1-166 from human CFL2 protein was used as the immunogen for the Cofilin 2 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Cofilin 2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Cofilin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Cofilin 2 (CFL2)

    别名

    Cofilin 2

    背景

    Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous (F) Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser-3 by factors such as opsonized zymosan. Lim kinase 1, a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin.

    UniProt

    Q9Y281

    途径

    Caspase Cascade in Apoptosis
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