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CDC5L 抗体 (AA 1-148)

The 小鼠 单克隆 anti-CDC5L antibody is suitable to detect CDC5L in samples from 人. It has been validated for FACS 和 IHC (p).
产品编号 ABIN7868175
发货至: 中国
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Room 801-803
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Quick Overview for CDC5L 抗体 (AA 1-148) (ABIN7868175)

抗原

See all CDC5L 抗体
CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

适用

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宿主

  • 74
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小鼠

克隆类型

  • 54
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单克隆

标记

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This CDC5L antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PCRP-CDC5L-2C6
  • 抗原表位

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    AA 1-148

    原理

    CDC5L Antibody / Cell division cycle 5-like protein

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-148) from the human protein was used as the immunogen for the CDC5L antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the CDC5L antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CDC5L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

    别名

    CDC5L

    背景

    Cdc5L (cell division cycle 5-like protein, pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3' splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation (t 6,19,p21,q13.1) with USF-2.

    UniProt

    Q99459

    途径

    Activation of Innate immune Response, Chromatin Binding
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