CDC5L 抗体 (AA 1-148)
Our Local Distributor
北京 101111
Quick Overview for CDC5L 抗体 (AA 1-148) (ABIN7868174)
抗原
See all CDC5L 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- AA 1-148
-
原理
- CDC5L Antibody / Cell division cycle 5-like protein (azide and preservative free)
-
纯化方法
- Protein A/G affinity
-
免疫原
- A recombinant partial protein sequence (within amino acids 1-148) from the human protein was used as the immunogen for the CDC5L antibody.
-
亚型
- IgG2a, kappa
-
-
-
-
应用备注
- Optimal dilution of the CDC5L antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- -20 °C
-
储存方法
- Aliquot the CDC5L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))
-
别名
- CDC5L
-
背景
- Cdc5L (cell division cycle 5-like protein, pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3' splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation (t 6,19,p21,q13.1) with USF-2.
-
UniProt
- Q99459
-
途径
- Activation of Innate immune Response, Chromatin Binding
抗原
-